Benzyl Bromide → HCID 11529646, Verbindung
Reaktionsgleichung
COC1C=C(OC)C=CC=1C[O:6][N:7]1[C:12](=[O:13])[C:11]2[O:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:10]=2[NH:9][C:8]1=[O:21].[CH2:28](Br)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH2:28]([N:9]1[C:10]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[O:14][C:11]=2[C:12](=[O:13])[N:7]([OH:6])[C:8]1=[O:21])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1Komponenten
3
Versuchsvorschrift
Following general procedure B2 and D1, 3-(2,4-Dimethoxy-benzyloxy)-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-dione was alkylated with benzyl bromide and subsequently deprotected to provide the title compound as a white solid. 1H NMR (d6-DMSO, 300 MHz) δ 5.57 (s, 2H); 7.22-7.39 (m, 6H); 7.61 (dd, J=8 Hz, 1H); 7.78-7.82 (m, 2H); Ret. time=2.36 min., m/z=309.0.
Quellen und Nachweise
- ORD-Eintrag
- ord-0d45b65999a444fc9aeb9c045fb205b0
- Quelldatensatz
- uspto-grants-2011_05