HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → 4-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | 2,4-Dichlorobenzyl chloride | HCID 7212 | — |
| Edukt | 4-Amino-2-chlorobenzoic acid | HCID 17154 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid | HCID 21836975 | — |
Reaktionsschritte
To a stirred mixture of 5.19 g of 2-chloro-4-aminobenzoic acid in 150 ml of methylene chloride is added 7.86 g of N,N-diisopropylethylamine and 12.67 g of 2,4-dichlorobenzylchloride and stirring continued for 18 hours. Water is added to the filtrate and the organic layer dried with Na2SO4 and concentrated in vacuo to give 13.68 g of the desired product, m.p. 171°-175° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05624923 |
| Quelldatensatz | uspto-grants-1997_04 |
| ORD ID | ord-2c6344183756424e98f2f44acba664c9 |
| Quellennotiz | uspto-grants-1997_04 |