Hydrogen Bromide → 4-Bromo-6-methylpyridine-2-carboxylic acid

HRID 552483Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 552483
[CH3:1][C:2]1[N:7]=[C:6]([C:8]([OH:10])=[O:9])[CH:5]=[C:4]([N+]([O-])=O)[CH:3]=1.[BrH:14]>>[Br:14][C:4]1[CH:3]=[C:2]([CH3:1])[N:7]=[C:6]([C:8]([OH:10])=[O:9])[CH:5]=1

Komponenten

3

Edukt 2

HCID 260Hydrogen BromideHCID 112753916-methyl-4-nitropicolinic acid

Produkt 1

HCID 534852954-Bromo-6-methylpyridine-2-carboxylic acid

Versuchsvorschrift

A solution of 3.6 g (19.6 mmol) of 6-Methyl-4-nitro-pyridine-2-carboxylic acid in 40 ml of 48% hydrobromic acid was heated at 100° C. overnight and then allowed to cool to room temperature. The solution was then evaporated to dryness in vaccuo. The crude material (10.5 g) containing inorganic salts was directly used in the next step.

Aufarbeitung

  1. customThe solution was then evaporated to dryness in vaccuo
  2. additionThe crude material (10.5 g) containing inorganic salts

Quellen und Nachweise

ORD-Eintrag
ord-7534d19fc07f4379a371d23045f25060
Quelldatensatz
uspto-grants-2011_05
Patentnummer
US07951824B2

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