HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-4-chloropyrimidine → 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid (4-chloro-pyrimidin-2-yl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-4-chloropyrimidine | HCID 223332 | — |
| Edukt | 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester | HCID 67163999 | — |
| Produkt | 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid (4-chloro-pyrimidin-2-yl)-amide | HCID 86614589 | — |
Reaktionsschritte
The title compound, was prepared from 4-(3,5-Difluorophenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 4-Chloro-pyrimidin-2-ylamine instead of 3-chloroaniline to yield the final compound as a light brown solid, MS (ISP): m/e=361.1, 363.2 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07951824B2 |
| Quelldatensatz | uspto-grants-2011_05 |
| ORD ID | ord-9a70d44ea71045e0b53d97fe731dc54b |
| Quellennotiz | uspto-grants-2011_05 |