2,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone → Wrypvzdhvrcrog-xjksgupxsa-

HRID 552778Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 552778
[C:1]([O:9][C@@H:10]1[C@H:16](OC(=O)C2C=CC=CC=2)[C@@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C@H:14]([CH3:35])[O:13][C:11]1=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CCN(CC)CC.C(Cl)(Cl)Cl>[C:1]([O:9][C:10]1[C:11]([O:13][C@@H:14]([CH3:35])[C@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:16]=1)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 1

HCID 112368422,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone

Produkt 1

HCID 11221893Wrypvzdhvrcrog-xjksgupxsa-Ausbeute 65 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 18929042Triethylamine chloroformLösungsmittel

Versuchsvorschrift

The compound (VII) (13.2 g, 27.8 mmol) is dissolved in Et3N:CHCl3 (1:4, 500 ml) under N2 current and stirred for 16 hours at a room temperature. After the reaction is finished, it is washed by water. An organic layer is dried using anhydrous MgSO4. The solution is vacuum concentrated and then the compound (VIII) (6.37 g, 65%) is isolated using flash column chromatography (toluene/EtOAc, 10:1, v/v).

Aufarbeitung

  1. washit is washed by water
  2. customAn organic layer is dried
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-783d157677b94e8e8c941b17c8656409
Quelldatensatz
uspto-grants-2011_05
Patentnummer
US07951839B2

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