N,N'-Diphenylformamidine → 3-methyl-2-((E)-2-phenylamino-vinyl)-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

HRID 553022

Reaktionsgleichung

Reaktionsgleichung von HRID 553022
[Na+:1].[CH3:2][C:3]1[C:11]([CH3:19])([CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:17])=[O:16])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]=1[CH2:20][CH2:21][CH2:22][S:23]([OH:26])(=[O:25])=[O:24].[C:27]1([NH:33][CH:34]=NC2C=CC=CC=2)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>CO>[Na+:1].[CH3:19][C:11]1([CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:16])=[O:17])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]([CH2:20][CH2:21][CH2:22][S:23]([OH:26])(=[O:24])=[O:25])=[C:3]1/[CH:2]=[CH:34]/[NH:33][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Komponenten

4

Edukt 2

HCID 94888N,N'-DiphenylformamidineHCID 866399822,3-dimethyl-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

Produkt 1

HCID 866399813-methyl-2-((E)-2-phenylamino-vinyl)-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

0.822 g (2 mmol) 2,3-dimethyl-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt 7 and 0.49 g (2.5 mmol) N,N′-diphenyl-formamidine are dissolved in 20 ml methanol and stirred for about four hours under reflux. The solvent is removed in vacuum after cooling to room temperature. The residue is washed carefully with ethyl acetate. A dark yellow solid is obtained which is processed without further purification.

Aufarbeitung

  1. temperatureunder reflux
  2. customThe solvent is removed in vacuum
  3. washThe residue is washed carefully with ethyl acetate
  4. customA dark yellow solid is obtained which
  5. customis processed without further purification

Quellen und Nachweise

ORD-Eintrag
ord-1fb798efe658416a8eba39e595841675
Quelldatensatz
uspto-grants-2011_05
Patentnummer
US07951959B2

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