2-Bromophenylacetic acid → (4'-{4-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Bromophenylacetic acid	HCID 87754	—
Edukt	{3-Methyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-isoxazol-4-yl}-carbamic acid 1-(2-chloro-phenyl)-ethyl ester	HCID 67350448	—
Produkt	(4'-{4-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid	HCID 46239907	—

Reaktionsschritte

Prepared according to the procedure described in Example 19, Step 1 using {3-methyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-isoxazol-4-yl}-carbamic acid 1-(2-chloro-phenyl)-ethyl ester and 2-bromophenylacetic acid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08048902B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-8d32c2cd3b484265b1c4a5c542a7d255
Quellennotiz	uspto-grants-2011_11