HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tosylmethyl isocyanide → Ethyl 4-methyl-1h-pyrrole-3-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tosylmethyl isocyanide | HCID 161915 | — |
| Edukt | Ethyl trans-crotonate | HCID 429065 | — |
| Edukt | Potassium tert-butoxide | HCID 23665647 | — |
| Produkt | Ethyl 4-methyl-1h-pyrrole-3-carboxylate | HCID 235044 | 71,1% |
Reaktionsschritte
Using p-toluenesulfonylmethyl isocyanide (8.55 g), ethyl crotonate (5.0 g) and potassium tert-butoxide (5.90 g), a procedure as in Reference Example 39 was performed to give the title compound as a pale-yellow solid (yield 4.77 g, 71%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08048909B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-c31a5c841b6e47ee8805ad48720a6c35 |
| Quellennotiz | uspto-grants-2011_11 |