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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 554784Erstellt: 25. Oktober 2026

methyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoate → Methyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoate

https://huagongshe.com/reaction/554784

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Eduktmethyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoateHCID 57670914—
Edukt3-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acidHCID 57671085—
Edukt4-(Tert-butoxycarbonyl)benzenesulfonamideHCID 59733636—
EduktTert-butyl 3-sulfamoylbenzoateHCID 59733695—
Edukt4-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acidHCID 66934750—
ProduktMethyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoateHCID 57670935—

Reaktionsschritte

4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acid, synthesized by using 4-(tert-butoxycarbonyl)benzenesulfonamide instead of the starting material compound of Example 198, that is, 3-(tert-butoxycarbonyl)benzenesulfonamide for the similar procedure as in Example 198, was used instead of the starting material of Example 208, that is, the compound 196, for the similar procedure as with Example 208 to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08049006B2
Quelldatensatzuspto-grants-2011_11
ORD IDord-c247d0df2ff7430a8a09e4602f7f8e44
Quellennotizuspto-grants-2011_11