2-Aminopyridine → 6-(5-Chloro-2-methoxybenzyl)-3,7-dioxo-n-{(1r)-1-[(2-pyridylamino)carbonyl]propyl}-1,4-diazepan-1-carboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Aminopyridine	HCID 10439	—
Edukt	Glycine tert-butyl ester hydrochloride	HCID 2725036	—
Edukt	Tert-butyl {[2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}acetate	HCID 76588771	—
Produkt	6-(5-Chloro-2-methoxybenzyl)-3,7-dioxo-n-{(1r)-1-[(2-pyridylamino)carbonyl]propyl}-1,4-diazepan-1-carboxamide	HCID 57671142	—

Reaktionsschritte

Instead of the starting material compound of Example 220, that is, glycine tert-butyl ester hydrochloride, 2-aminopyridine was used for the similar procedure as in Example 220 to obtain the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08049006B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-a0055453a1a64e6d87578aa860231b7c
Quellennotiz	uspto-grants-2011_11