HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → (+/-)-1-Oxiranylmethyl-4-(3-phenyl-propyl)-piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate | HCID 286836 | — |
| Edukt | 1-(3-Phenylpropyl)piperazine | HCID 796534 | — |
| Produkt | (+/-)-1-Oxiranylmethyl-4-(3-phenyl-propyl)-piperazine | HCID 17810519 | 80% |
Reaktionsschritte
The same method as employed in the preparation of Intermediate 1 but starting from 1-(3-phenylpropyl)-piperazine and 3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after Biotage chromatography the title compound as a yellow oil in a 80% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08053436B1 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-a7606830c6ef40fa8c593f3e47f355cc |
| Quellennotiz | uspto-grants-2011_11 |