(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → (+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate	HCID 286836	—
Edukt	1-(Cyclohexylmethyl)piperazine	HCID 2735885	—
Produkt	(+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine	HCID 86661984	92%

Reaktionsschritte

The same method as employed in the preparation of Intermediate 1 but starting from 1-cyclohexylmethyl piperazine and (±)-3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after flash chromatography the title compound as a yellow oil in a 92% yield.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08053436B1
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-2b93a9fd214047b3ae7e3a165f7700a8
Quellennotiz	uspto-grants-2011_11