2,6-Dimethylphenol → Oxalic acid (2,6-dimethyl-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) ester

HRID 55563

Reaktionsgleichung

Reaktionsgleichung von HRID 55563
[O:1]=[C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:13]=[C:14]([O:17][C:18](=[O:22])[C:19](Cl)=[O:20])[CH:15]=[CH:16][C:4]=2[O:3]1.[CH3:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH3:30])[C:25]=1[OH:31]>C1(C)C=CC=CC=1>[O:1]=[C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:13]=[C:14]([O:17][C:18](=[O:22])[C:19]([O:31][C:25]3[C:26]([CH3:30])=[CH:27][CH:28]=[CH:29][C:24]=3[CH3:23])=[O:20])[CH:15]=[CH:16][C:4]=2[O:3]1

Komponenten

4

Edukt 2

HCID 113352,6-DimethylphenolHCID 53805502Chloro-oxo-acetic acid 2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl ester

Produkt 1

HCID 86750782Oxalic acid (2,6-dimethyl-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) esterAusbeute 38 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Reaction of chloro-oxo-acetic acid 2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl ester prepared as Example 11 reacted in toluene at the reflux with 2,6-dimethylphenol gave after purification oxalic acid (2,6-dimethyl-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) ester (38% yield). Analysis C,70.6; H,4.1; C24H18O6 requires C,71.8; H,4.2%. Mass Spectrometry shows a molecular ion at 402.

Aufarbeitung

  1. customgave

Quellen und Nachweise

ORD-Eintrag
ord-2a196affa26c4881b64d27224525a5b9
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05625080

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