4-(5-Methyl-1,2,4-oxadiazol-3-yl)aniline → 2-((1R,2S)-2-aminocyclohexylamino)-4-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino) pyrimidine-5-carboxamide

HRID 559020Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 559020
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19](C3ON=CC=3)=[CH:18][CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[CH3:30][C:31]1[O:35][N:34]=[C:33](C2C=CC(N)=CC=2)[N:32]=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([C:33]3[N:32]=[C:31]([CH3:30])[O:35][N:34]=3)=[CH:18][CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

Komponenten

3

Edukt 2

HCID 181881764-(5-Methyl-1,2,4-oxadiazol-3-yl)anilineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

Produkt 1

HCID 461843702-((1R,2S)-2-aminocyclohexylamino)-4-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino) pyrimidine-5-carboxamide

Versuchsvorschrift

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 4-(5-methyl-1,2,4-oxadiazol-3-yl)aniline in step 1. MS: 409.5 (M+H).

Aufarbeitung

  1. customThis compound was synthesised

Quellen und Nachweise

ORD-Eintrag
ord-a6c175c98e2d46c59455871644db79be
Quelldatensatz
uspto-grants-2011_11
Patentnummer
US08063058B2

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