HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → Trifluoroacetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | 2-(Boc-amino)-4-methylthiophene | HCID 57471983 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Trifluoroacetic acid | HCID 6422 | — |
| Produkt | 4-Methylthiophen-2-amine | HCID 12231192 | — |
Reaktionsschritte
A solution of tert-butyl 4-methylthiophen-2-ylcarbamate (0.880 g, 4.13 mmol) in CH2Cl2 (8 mL) and TFA (6 mL) wad stirred at room temperature for 3 h. Solvents was removed in vacuo to give 4-methylthiophen-2-amine as trifluoroacetic acid salt (0.920 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08063058B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-65f76d5720c6418f9833905f967babde |
| Quellennotiz | uspto-grants-2011_11 |