HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Aminothiazole → 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Aminothiazole | HCID 2155 | — |
| Edukt | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| Edukt | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | — |
| Produkt | 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea | HCID 59733095 | 72% |
| Produkt | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | 35% |
Reaktionsschritte
(2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (843 g, 35%) was prepared from 2-amino-5-methyl-benzoic acid (1.51 g, 0.1 mol) following the general procedure S. 1-[2-(2-methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea (132 mg, 72%) was prepared from (2-amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (121 mg, 0.5 mmol) and 2-aminothiazole (0.060 g, 0.6 mmol) following the general procedure D.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08063081B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-2b571ccbdc1c44d591f7aca6887fd956 |
| Quellennotiz | uspto-grants-2011_11 |