5-Methylimidazo[2,1-b][1,3]thiazole-6-carboxylic acid → HCID 66998869, Verbindung
Reaktionsgleichung
[NH2:1][CH2:2][C@H:3]1[N:8]([C:9]([C:11]2[N:12]=[C:13]([CH3:23])[S:14][C:15]=2[C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[O:10])[CH2:7][C@H:6]2[C@@H:4]1[CH2:5]2.[CH3:24][C:25]1[N:32]2[C:28]([S:29][CH:30]=[CH:31]2)=[N:27][C:26]=1[C:33](O)=[O:34]>>[CH3:23][C:13]1[S:14][C:15]([C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[C:11]([C:9]([N:8]2[CH2:7][C@H:6]3[C@H:4]([CH2:5]3)[C@H:3]2[CH2:2][NH:1][C:33]([C:26]2[N:27]=[C:28]3[N:32]([C:25]=2[CH3:24])[CH:31]=[CH:30][S:29]3)=[O:34])=[O:10])[N:12]=1Komponenten
3
Versuchsvorschrift
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 5-Methyl-imidazo[2,1-b]thiazole-6-carboxylic acid. LC-MS (basic): tR=0.84 min; [M+H]+=491.9.
Quellen und Nachweise
- ORD-Eintrag
- ord-7e1a1ab6944f4b45b8dea5ed2af749f4
- Quelldatensatz
- uspto-grants-2011_11