Ethyl 3-(1-benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propanoate → 3-(1-Benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propan-1-ol
Reaktionsgleichung
[S:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([C:17]3[C:25]4[C:20](=[C:21]([CH2:26][S:27][CH3:28])[CH:22]=[CH:23][CH:24]=4)[NH:19][CH:18]=3)[CH2:11][C:12](OCC)=[O:13])=[CH:9][C:4]=2[CH:3]=[CH:2]1.ClC1C=CC(C(C2C3C(=C(CSC)C(F)=CC=3)NC=2)CCO)=CC=1>>[S:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([C:17]3[C:25]4[C:20](=[C:21]([CH2:26][S:27][CH3:28])[CH:22]=[CH:23][CH:24]=4)[NH:19][CH:18]=3)[CH2:11][CH2:12][OH:13])=[CH:9][C:4]=2[CH:3]=[CH:2]1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared starting from 1.17 g (2.87 mmol) of the compound from Example 49A in analogy to the synthesis of the compound from Example 16. 0.93 g (88% of theory) of the title compound were obtained.
Aufarbeitung
- custom