Ammonia → HCID 117966096, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([NH:23][C:24](=[O:29])[CH2:25][C:26](=O)[CH3:27])[CH:5]=[CH:6][C:7]=1[NH:8][C:9]([CH3:22])([CH3:21])[CH2:10][C:11]1[CH:20]=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=1.[NH3:30]>CO>[NH2:30]/[C:26](/[CH3:27])=[CH:25]\[C:24]([NH:23][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9]([CH3:21])([CH3:22])[CH2:10][C:11]2[CH:20]=[CH:19][C:18]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:12]=2)=[C:2]([Cl:1])[CH:3]=1)=[O:29]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of N-(3-chloro-4-((2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino) phenyl)-3-oxobutanamide (2.0 g, 4.89 mmol), MeOH (15 mL) and ammonia (15 mL) was stirred at rt overnight. The mixture was then concentrated in vacuo to give the title compound, which was used for next step without further purification.