Ammonia → HCID 90030960, Verbindung
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[C:5]([CH:24]=[CH:25][CH:26]=1)[O:6][CH2:7][N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([NH:17][C:18](=[O:23])[CH2:19][C:20](=O)[CH3:21])[CH:15]=2)[CH:10]=[CH:9]1)#[N:2].[NH3:27]>CO>[NH2:27]/[C:20](/[CH3:21])=[CH:19]\[C:18]([NH:17][C:14]1[CH:15]=[C:16]2[C:11]([CH:10]=[CH:9][N:8]2[CH2:7][O:6][C:5]2[CH:24]=[CH:25][CH:26]=[C:3]([C:1]#[N:2])[CH:4]=2)=[CH:12][CH:13]=1)=[O:23]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of N-(1-((3-cyanophenoxy)methyl)-1H-indol-6-yl)-3-oxobutanamide (1.04 g, 2.99 mmol), MeOH (20 mL) and ammonia (20 mL) was stirred at rt overnight. The mixture was concentrated in vacuo to give the title compound, which was used for next step without further purification.
Aufarbeitung
- concentration