Pentamethylbenzene → Methyl 2-(3-cyano-4-hydroxyphenyl)isonicotinate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Pentamethylbenzene	HCID 12784	—
Edukt	Methyl 2-[4-(benzyloxy)-3-cyanophenyl]isonicotinate	HCID 66995135	—
Lösungsmittel	Trifluoroacetic acid	HCID 6422	—
Produkt	Methyl 2-(3-cyano-4-hydroxyphenyl)isonicotinate	HCID 136368377	—

Reaktionsschritte

Methyl 2-[4(benzyloxy)-3-cyanophenyl]isonicotinate and pentamethylbenzene were heated under reflux temperature in trifluoroacetic acid to obtain methyl 2-(3-cyano-4-hydroxyphenyl)isonicotinate. F: 255.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08067446B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-b435b5fd0d6c49fc90b0c27c34855dbd
Quellennotiz	uspto-grants-2011_11