2-Bromo-5-nitrobenzoic acid → (2-Bromo-5-nitrophenyl)methanol

HRID 563537Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 563537
[Br:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4](O)=[O:5].O1CCCC1.B>>[Br:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[CH2:4][OH:5]

Komponenten

3

Edukt 2

HCID 2430252-Bromo-5-nitrobenzoic acidHCID 2723981Borane;tetrahydrofuran

Produkt 1

HCID 18671373(2-Bromo-5-nitrophenyl)methanol

Versuchsvorschrift

To 2-bromo-5-nitrobenzoic acid (5 g, 20 mmol) at 0° C. was added borane tetrahydrofuran complex (1 M in THF; 200 mL, 200 mmol), and the reaction was stirred at room temperature overnight. The mixture was quenched with 1N aqueous HCl to give the title compound.

Aufarbeitung

  1. customThe mixture was quenched with 1N aqueous HCl

Quellen und Nachweise

ORD-Eintrag
ord-10610fa9968e4d3ba8c45c75675bc868
Quelldatensatz
uspto-grants-2011_11
Patentnummer
US08067445B2

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