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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 563785Erstellt: 24. Oktober 2026

5-Bromo-2-fluorobenzaldehyde → (5-Bromo-2-fluorophenyl)methanol

https://huagongshe.com/de/reaction/563785

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-Bromo-2-fluorobenzaldehydeHCID 736327—
EduktSodium borohydrideHCID 4311764—
LösungsmittelMethanolHCID 887—
Produkt(5-Bromo-2-fluorophenyl)methanolHCID 2773352—

Reaktionsschritte

To a solution of 5-bromo-2-fluorobenzaldehyde (1.3 g, 6.4 mmol) in MeOH (10 mL) was added sodium borohydride (0.29 g, 7.7 mmol), and the reaction was stirred at room temperature for 5 minutes. After aqueous work-up, the residue was purified by silica gel chromatography to give the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08067445B2
Quelldatensatzuspto-grants-2011_11
ORD IDord-e013470df19541eaa101c5ba8cb8d399
Quellennotizuspto-grants-2011_11