HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → 2-(5-Bromo-2-fluorophenyl)acetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | 2-(5-Bromo-2-fluorophenyl)acetonitrile | HCID 23509631 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 2-(5-Bromo-2-fluorophenyl)acetic acid | HCID 3584690 | — |
Reaktionsschritte
(5-Bromo-2-fluoro-phenyl)-acetonitrile (0.5 g, 2.3 mmol) was treated with acetic acid (2 mL) and sulfuric acid (2 mL) in H2O (2 mL) at 95° C. for 5 hours. Aqueous worked-up afforded the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08067445B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-77d85f3bebe94d1f845b7646e2bfdd2d |
| Quellennotiz | uspto-grants-2011_11 |