Diisopropylamine → 2-(3-(Di(propan-2-yl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Diisopropylamine	HCID 7912	—
Edukt	3,4-Dihydro-2-hydroxy-4-phenyl-2H-1-benzopyran-6-methanol	HCID 54761596	—
Lösungsmittel	Methanol	HCID 887	—
Produkt	2-(3-(Di(propan-2-yl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenol	HCID 9927971	—

Reaktionsschritte

(2-Hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl)methanol (Example 13, 830 g, 3.24 mol, 1.0 eq) was stirred in methanol (4150 mL, 5.0 mL/g). Diisopropylamine (1362 mL, 9.72 mol, 3.0 eq) was then added over 15 minutes via dropping funnel. The resulting solution was then stirred for one hour under nitrogen.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08067594B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-3e8a149aa00f423f98cf6e4e37a05860
Quellennotiz	uspto-grants-2011_11