HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylate → Tert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylate | HCID 57813409 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | Tert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylate | HCID 57813365 | 94,4% |
Reaktionsschritte
To a solution of 1,1-dimethylethyl 4-[(3-bromophenyl)methylidene]-1-piperidinecarboxylate (201 mg, 0.571 mmol) in THF (1 mL) was applied onto H-Cube using 10% Pd/C at a flow rate of 1 mL/min and 1 atm H2. The mixture was concentrated to afford 0.1909 g (94%) of the title compound. LC-MS m/z 354 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08067408B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-df9fe245de054905bacedbd7e7a4ed5f |
| Quellennotiz | uspto-grants-2011_11 |