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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 564555Erstellt: 25. Oktober 2026

Tert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylate → Tert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/564555

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTert-butyl 4-(3-bromobenzylidene)piperidine-1-carboxylateHCID 57813409—
KatalysatorPalladiumHCID 23938—
LösungsmittelTetrahydrofuranHCID 8028—
ProduktTert-butyl 4-(3-bromobenzyl)piperidine-1-carboxylateHCID 5781336594,4%

Reaktionsschritte

To a solution of 1,1-dimethylethyl 4-[(3-bromophenyl)methylidene]-1-piperidinecarboxylate (201 mg, 0.571 mmol) in THF (1 mL) was applied onto H-Cube using 10% Pd/C at a flow rate of 1 mL/min and 1 atm H2. The mixture was concentrated to afford 0.1909 g (94%) of the title compound. LC-MS m/z 354 (M+H)+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08067408B2
Quelldatensatzuspto-grants-2011_11
ORD IDord-df9fe245de054905bacedbd7e7a4ed5f
Quellennotizuspto-grants-2011_11