HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Bromine | HCID 24408 | — |
| Edukt | Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)- | HCID 69772 | — |
| Edukt | HCID 178418368 | HCID 178418368 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide | HCID 22111802 | — |
Reaktionsschritte
This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06172239B2 |
| Quelldatensatz | uspto-grants-2001_01 |
| ORD ID | ord-32a7ae720a0443be803c1c7691394291 |
| Quellennotiz | uspto-grants-2001_01 |