HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 565875Erstellt: 24. Oktober 2026
3-Ethylpyridine → 3-Ethyl-1-[4-(7-phenyl-3,4-dihydronaphthalene-2-carboxamido)benzyl]pyridinium chloride
https://huagongshe.com/de/reaction/565875
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
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| Edukt | 3-Ethylpyridine | HCID 10823 | — |
| Edukt | N-[4-(chloromethyl)phenyl]-7-phenyl-3,4-dihydronaphthalene-2-carboxamide | HCID 10809385 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 3-Ethyl-1-[4-(7-phenyl-3,4-dihydronaphthalene-2-carboxamido)benzyl]pyridinium chloride | HCID 18472572 | — |
Reaktionsschritte
In DMF (3ml) was dissolved N-[4-(chloromethyl)-phenyl]-7-phenyl-3,4-dihydronaphthalene-2-carboxamide (160mg), and to the mixture was added 3-ethylpyridine (146 μl). The mixture was stirred at 70° C. for 72 hours and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate-methanol to give 3-ethyl-1-[4-(7-phenyl-3,4-dihydro-naphthalene-2-carboxamido)benzyl]pyridinium chloride (Compound 27) (185mg) as colorless crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US06172061B2 |
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| Quelldatensatz | uspto-grants-2001_01 |
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| ORD ID | ord-75034c94fa824187af8f66e1371f2476 |
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| Quellennotiz | uspto-grants-2001_01 |
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