4-Bromo-2-hydroxypyridine → tert-Butyl 2-(4-bromo-2-oxopyridin-1(2H)-yl)butanoate

Beteiligte Stoffe

Reaktionsschritte

348 mg (2.0 mmol) of 4-bromopyridin-2(1H)-one and 1.2 eq. of tert-butyl 2-bromobutanoate (racemate) were reacted according to General Method 4B at 120° C. After aqueous work-up, the desired product was reacted further as crude product. Yield: 608 mg (purity 82%, 79% of theory)

Herkunft & Nachweise