Ethanol → Ethyl 10-Bromodecanoate

HRID 566623

Reaktionsgleichung

Reaktionsgleichung von HRID 566623
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12].[CH2:14](O)[CH3:15]>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12]

Komponenten

3

Edukt 2

HCID 702EthanolHCID 14271210-Bromodecanoic Acid2×

Produkt 1

HCID 560452Ethyl 10-BromodecanoateAusbeute 98,6 %

Versuchsvorschrift

To this end, the 180.5 g of 10-bromodecanoic acid from Step II was added to the 11 reactor (described above) along with 645 g of absolute ethanol. The mixture was heated and stirred for about 3.5 h. GC analysis confirmed that reaction was completed when 10-bromodecanoic acid could not be detected. Next, excess ethanol and residual water were removed through evaporation leaving 197.8 g of 94.9% pure ethyl 10-bromodecanoate residue. 150 g MTBE was added to the ethyl 10-bromodecanoate residue which then was washed repeatedly with 10% sodium carbonate solution followed by water. The mixture was phase separated to obtain 340.7 g of a mixture of ethyl 10-bromodecanoate and MTBE. According to GC analysis the yield from Steps II and III was 89.7%.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. customGC analysis confirmed that reaction
  3. customNext, excess ethanol and residual water were removed through evaporation

Quellen und Nachweise

ORD-Eintrag
ord-743cfd1475e8481ba3391b1b90f473f5
Quelldatensatz
uspto-grants-2001_01
Patentnummer
US06175024B1

Verknüpfte Notizen

Wird geladen…