Ethyl bromoacetate → Ethyl 2-(4-bromo-2-oxopyridin-1(2H)-YL)acetate

HRID 56672

Reaktionsgleichung

[Br:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1.Br[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12]>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:4](=[O:8])[CH:3]=1

Komponenten

Edukt 2

HCID 7748Ethyl bromoacetate

HCID 8171154-Bromo-2-hydroxypyridine

Produkt 1

HCID 71009808Ethyl 2-(4-bromo-2-oxopyridin-1(2H)-YL)acetate

Versuchsvorschrift

5.0 g (28.7 mmol) of 4-bromopyridin-2(1H)-one and 5.3 g (31.6 mmol) of ethyl bromoacetate were reacted according to General Method 4B. Yield: 6.2 g (83% of theory)

Quellen und Nachweise

ORD-Eintrag: ord-3afa27d21b1c4117801cdffa704044f9
Quelldatensatz: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09434690B2

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