HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzeneethanamine, 4-nitro-, hydrochloride (1:1) → (s)-1-Phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzeneethanamine, 4-nitro-, hydrochloride (1:1) | HCID 458983 | — |
| Edukt | (2S)-2-(phenoxymethyl)oxirane | HCID 1534345 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | (s)-1-Phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol | HCID 53932073 | 39,3% |
Reaktionsschritte
7.71 g of (S)-2-phenoxymethyloxirane and 10.34 g of 2-(4-nitrophenyl)ethylamine hydrochloride were subjected to a ring-opening reaction in the presence of 5.20 g of triethylamine to obtain 6.35 g of (S)-1-phenoxy-3-[[2-(4-nitrophenyl)ethyl]amino]-2-propanol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06177454B1 |
| Quelldatensatz | uspto-grants-2001_01 |
| ORD ID | ord-2ee66b0f78b84c239bb91ff1932ac374 |
| Quellennotiz | uspto-grants-2001_01 |