Ammonium Chloride → allyl(1R,5S,6S)-2-[(3S,5S)-1-allyloxycarbonyl-5-[1-hydroxy-1-(imidazo[5,1-b]thiazol-7-yl)methyl]pyrrolidin-3-yl]thio-6-[(1R)-1-(t-butyldimethylsilyloxy)ethyl]-1-methylcarbapen-2-em-3-carboxylate

Reaktionsgleichung

C[Mg]I.C(OCC)C.I[C:10]1[N:11]=[CH:12][N:13]2[CH:17]=[CH:16][S:15][C:14]=12.[CH2:18]([O:21][C:22]([N:24]1[C@H:28]([CH:29]=[O:30])[CH2:27][C@H:26]([S:31][C:32]2[C@H:33]([CH3:56])[C@@H:34]3[C@@H:44]([C@H:45]([O:47][Si:48]([C:51]([CH3:54])([CH3:53])[CH3:52])([CH3:50])[CH3:49])[CH3:46])[C:43](=[O:55])[N:35]3[C:36]=2[C:37]([O:39][CH2:40][CH:41]=[CH2:42])=[O:38])[CH2:25]1)=[O:23])[CH:19]=[CH2:20].[Cl-].[NH4+]>C1COCC1>[CH2:18]([O:21][C:22]([N:24]1[C@H:28]([CH:29]([OH:30])[C:10]2[N:11]=[CH:12][N:13]3[CH:17]=[CH:16][S:15][C:14]=23)[CH2:27][C@H:26]([S:31][C:32]2[C@H:33]([CH3:56])[C@@H:34]3[C@@H:44]([C@H:45]([O:47][Si:48]([C:51]([CH3:54])([CH3:53])[CH3:52])([CH3:49])[CH3:50])[CH3:46])[C:43](=[O:55])[N:35]3[C:36]=2[C:37]([O:39][CH2:40][CH:41]=[CH2:42])=[O:38])[CH2:25]1)=[O:23])[CH:19]=[CH2:20]