HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Piperazine → 8-(4-Fluorobenzyl-amino)-4-(1-oxido-thiomorpholino)-2-piperazino-pyrimido-[5,4-d]-pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Piperazine | HCID 4837 | — |
| Edukt | 2-Chloro-8-(4-fluorobenzylamino)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine | HCID 12817038 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 8-(4-Fluorobenzyl-amino)-4-(1-oxido-thiomorpholino)-2-piperazino-pyrimido-[5,4-d]-pyrimidine | HCID 12817092 | — |
Reaktionsschritte
This compound was prepared analogous to Example 118 from 2-chloro-8-(4-fluorobenzylamino)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 210°-212° C.) and piperazine in dioxane at 80° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04728646 |
| Quelldatensatz | uspto-grants-1988_03 |
| ORD ID | ord-5c97865827a3488e8dcfa56419d3e9d1 |
| Quellennotiz | uspto-grants-1988_03 |