(E)-4-(1H-imidazol-1-yl)-2-butenamine → HCID 178456322, Verbindung

HRID 568491Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 568491
[N:1]1([CH2:6]/[CH:7]=[CH:8]/[CH2:9][NH2:10])[CH:5]=[CH:4][N:3]=[CH:2]1.[IH:11].CS[C:14]1[C:22]2[CH:23]=[CH:24][CH:25]=[C:20]3[C:21]=2[C:16](=[CH:17][CH:18]=[CH:19]3)[N:15]=1>C(O)C>[IH:11].[N:1]1([CH2:6]/[CH:7]=[CH:8]/[CH2:9][NH:10][C:14]2[C:22]3[CH:23]=[CH:24][CH:25]=[C:20]4[C:21]=3[C:16](=[CH:17][CH:18]=[CH:19]4)[N:15]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Komponenten

4

Edukt 2

HCID 13371079(E)-4-(1H-imidazol-1-yl)-2-butenamineHCID 201506502-Methylthiobenz(cd)indole hydriodide

Produkt 1

HCID 178456322HCID 178456322, VerbindungAusbeute 63,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
-10 °C

Versuchsvorschrift

A mixture of 5.0 g of (E)-4-(1H-imidazol-1-yl)-2-butenamine, 11.5 g of 2-(methylthio)benz[cd]indole hydroiodide and 400 ml of ethanol was stirred and heated at reflux for 16 hours, then clarified while hot. The filtrate was concentrated to 250 ml, cooled to -10° C. and the resulting solid collected, washed with ethanol, ether and dried at 60° C. in vacuo, giving 9.3 g of the desired product, mp 152°-155° C. (dec.).

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux for 16 hours
  3. concentrationThe filtrate was concentrated to 250 ml
  4. customthe resulting solid collected
  5. washwashed with ethanol, ether
  6. customdried at 60° C. in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-68081b6f88f141f8bbfdbcfad243a3dd
Quelldatensatz
uspto-grants-1988_03
Patentnummer
US04728663

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