HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaR)- → (R)alpha-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaR)- | HCID 156232 | — |
| Edukt | (1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]cyclopropane-carboxylic acid | HCID 86740318 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | (R)alpha-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate | HCID 86740317 | — |
Reaktionsschritte
Using the procedure of Step F of Example 9, (1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]cyclopropane-carboxylic acid and (R)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain (R)α-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+117.5°±3° (c=0.6% in chloroform).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04732903 |
| Quelldatensatz | uspto-grants-1988_03 |
| ORD ID | ord-f8691d46e87b4c4eb87a915cb6409b11 |
| Quellennotiz | uspto-grants-1988_03 |