HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diisobutylaluminum hydride → (1H-indol-5-yl)methanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diisobutylaluminum hydride | HCID 14487 | — |
| Edukt | methyl 1H-indole-5-carboxylate | HCID 2737635 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | (1H-indol-5-yl)methanol | HCID 2773458 | — |
Reaktionsschritte
96 g (0.548 mole) of 6b are treated analogously to Example 1a in 1,800 ml of ether and 1,391 ml (1.67 moles) of DIBAL (1.2 molar in toluene). After chromatography on silica gel with gradient elution with petroleum ether/ethyl acetate (3:1) and petroleum ether/ethyl acetate (1:1), 39.3 g (49%) of pure product are obtained. C9H9NO (147.2)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04734407 |
| Quelldatensatz | uspto-grants-1988_03 |
| ORD ID | ord-bc1b83dde3684cc4aa27d378a6abf204 |
| Quellennotiz | uspto-grants-1988_03 |