2-(Trifluoromethyl)acrylic acid → 3-Acetylthio-2-trifluoromethylpropanoic acid

Beteiligte Stoffe

Reaktionsschritte

A mixture of thiolactic acid (50 g.) and 2-(trifluoromethyl)acrylic acid [M. W. Buxton, et al., J. Chem. Soc., 366 (1954)] (66 g.) is heated on the steam bath for one hour and then stored at room temperature for eighteen hours. The reaction mixture is distilled in vacuo to give 3-acetylthio-2-trifluoromethylpropanoic acid.

Herkunft & Nachweise