Hydrazine → HCID 178434195, Verbindung

HRID 569903

Reaktionsgleichung

Reaktionsgleichung von HRID 569903
[C:1]([CH:4]1[C:9](=[O:10])[CH2:8][CH2:7][CH2:6][C:5]1=O)(=O)[CH3:2].[NH2:12][NH2:13]>CO>[CH3:2][C:1]1[C:4]2[C:9](=[O:10])[CH2:8][CH2:7][CH2:6][C:5]=2[NH:13][N:12]=1

Komponenten

4

Edukt 2

HCID 9321HydrazineHCID 1381042-Acetyl-1,3-cyclohexanedione

Produkt 1

HCID 178434195HCID 178434195, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

To an ice-cold solution of 33.3 grams of 2-acetyl-1,3-cyclohexanedione in 400 ml of methanol was added dropwise a solution of 7.2 ml of hydrazine in 50 ml of methanol and the resulting reaction mixture was heated at reflux for 20 hours. The solvent was then removed under reduced pressure and the residue was triturated in ethyl ether to give 1,5,6,7-tetrahydro-3-methyl-4H-indazol-4-one as a yellow crystalline solid melting at about 154°-157° C.

Aufarbeitung

  1. customthe resulting reaction mixture
  2. temperaturewas heated
  3. temperatureat reflux for 20 hours
  4. customThe solvent was then removed under reduced pressure
  5. customthe residue was triturated in ethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-494d869e6cbc42cf8d34d3dae1d77716
Quelldatensatz
uspto-grants-1988_03
Patentnummer
US04734430

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