Benzyl Bromide → 4-Keto-1-[(phenylmethoxy)carbonyl]-L-proline benzyl ester

Beteiligte Stoffe

Reaktionsschritte

5 g (0.02 mmol) of 4-keto-1-[(phenylmethoxy)carbonyl]-L-proline was dissolved in 50 ml dimethylformamide, 2.62 ml (0.022 mmol) of benzyl bromide and 3.59 g (0.026 mmol) of potassium carbonate were added. The reaction mixture was stirred for 1 hour followed by normal extractive work to give the title compound, 3.5 gm (49% yield), m.p. 55°-56° C.

Herkunft & Nachweise