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HRID 570389Erstellt: 26. Oktober 2026

Methyl 2-amino-3-thenoate → 2-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-3-carboxylic acid

https://huagongshe.com/reaction/570389

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl 2-amino-3-thenoateHCID 78381—
Edukt3-(1H-pyrrolo[2,3-b]pyridin-4-ylamino)thiophene-2-carboxylic acidHCID 66957440—
Produkt2-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-3-carboxylic acidHCID 66957991—

Reaktionsschritte

This compound was prepared in an analogous manner as 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid using methyl 2-aminothiophene-3-carboxylate instead of methyl 3-aminothiophene-2-carboxylate.). LCMS (ESI) 260 (M+H) 1H NMR (400 MHz, DMSO-d6) δ ppm 11.88 (1H, br. s.) 10.77 (1H, s) 8.16 (1H, d, J=5.66 Hz) 7.41 (1H, dd, J=3.22, 1.85 Hz) 7.23 (1H, d, J=5.86 Hz) 7.01 (1H, d, J=5.86 Hz) 6.94 (1H, d, J=5.66 Hz) 6.47 (1H, d, J=2.73 Hz)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09023847B2
Quelldatensatzuspto-grants-2015_05
ORD IDord-5dcb5c2dff4b450d818842d4e6812ad7
Quellennotizuspto-grants-2015_05