Ethyl trifluoroacetate → HCID 58587431, Verbindung

HRID 570561Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 570561
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][NH2:6].[F:7][C:8]([F:15])([F:14])[C:9](OCC)=[O:10]>C(#N)C>[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][NH:6][C:9](=[O:10])[C:8]([F:15])([F:14])[F:7]

Komponenten

4

Edukt 2

HCID 9794Ethyl trifluoroacetateHCID 80511N-Methyl-1,3-propanediamine

Produkt 1

HCID 58587431HCID 58587431, VerbindungAusbeute 98,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Reaktionsbedingungen

Temperatur
85 °C

Versuchsvorschrift

N-Methyl-1,3-diaminopropane (50 g, 0.56 mol) was dissolved in 200 mL acetonitrile followed by addition of ethyl trifluoroacetate (154 ml, 1.28 mol). The reaction mixture was stirred overnight at 85° C. The solvent was then removed in vacuo to yield the depicted product as a brown oil (101 g, 98.5%).

Aufarbeitung

  1. customThe solvent was then removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-3516ee60e9e04bb8ae2c19f4017f88b5
Quelldatensatz
uspto-grants-2015_05
Patentnummer
US09023860B2

Notizen zur Reaktion

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