Sodium Hydroxide → (2,6-Diethyl-4-methylphenyl)glyoxylic acid
Reaktionsgleichung
[CH2:1]([C:3]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:4]=1[C:12](=[O:18])[C:13]([O:15]CC)=[O:14])[CH3:2].[OH-].[Na+]>O1CCCC1>[CH2:10]([C:5]1[CH:6]=[C:7]([CH3:9])[CH:8]=[C:3]([CH2:1][CH3:2])[C:4]=1[C:12](=[O:18])[C:13]([OH:15])=[O:14])[CH3:11]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of ethyl (2,6-diethyl-4-methylphenyl)glyoxylate (320.82 g) in tetrahydrofuran (600 ml) was added 10.7 weight % of aqueous sodium hydroxide solution (900 ml) dropwise at 10° C. of the internal temperature over 2 hours. The resulting mixture was stirred at room temperature for 1 hour. Then, the organic layer was evaporated, and the aqueous layer was washed with tert-butyl methyl ether. To the aqueous layer was added concentrated hydrochloric acid (180 ml) dropwise, and extracted with tert-butyl methyl ether. The organic layer was concentrated under reduced pressure to give 166.55 g of (2,6-diethyl-4-methylphenyl)glyoxylic acid.