[OH-].[K+].[C:3]([O:12]CC)(=[O:11])[CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10].Cl>CCCCCCC>[C:3]([OH:12])(=[O:11])[CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10]A20% aqueous solution of potassium hydroxide (477 g, 1.7 mol) and ethyl 4,6-octadienoate (c) (114.4 g, 0.68 mol) were put into a four-neck flask, followed by stirring at 45° C. for 3 hours. The reaction solution was cooled to room temperature, heptane (230 mL) was added thereto, and 35% hydrochloric acid (177 g) was added dropwise thereto. After separation of liquid, the organic layer was washed with water (230 mL), and the solvent was evaporated therefrom under a reduced pressure. Thus, 4,6-octadienoic acid (d) was obtained (90.6 g, yield 95%).
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