Thionyl Chloride → 2-(Chloromethyl)-4H-1-benzopyran-4-one

HRID 574123Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 574123
O[CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.S(Cl)([Cl:16])=O>C(Cl)(Cl)Cl>[Cl:16][CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 12536095HCID 12536095, Verbindung

Produkt 1

HCID 140019552-(Chloromethyl)-4H-1-benzopyran-4-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

The 2-(hydroxymethyl)-4H-chromen-4-one was dissolved in 30 ml of anhydrous chloroform at room temperature, 1 ml of thionyl chloride was added to the solution, and reaction mixture was stirred at room temperature for 24 hours. The solvent was thereafter evaporated, and the obtained liquid was dissolved in anhydrous hexane, which was also evaporated again to give 2-(chloromethyl)-4H-chromen-4-one which was further reacted without purification.

Aufarbeitung

  1. customThe solvent was thereafter evaporated
  2. dissolutionthe obtained liquid was dissolved in anhydrous hexane
  3. customwhich was also evaporated again

Quellen und Nachweise

ORD-Eintrag
ord-31677ca7dbbc4e74bc58de3ddaf5d14c
Quelldatensatz
uspto-grants-2015_05
Patentnummer
US09034872B2

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