Thionyl Chloride → 4-Methylnaphthalene-1-carbonyl chloride

HRID 574598Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 574598
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([OH:14])=O)=[CH:4][CH:3]=1.S(Cl)([Cl:17])=O>ClCCl>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([Cl:17])=[O:14])=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 30142854-Methyl-1-naphthalenecarboxylic acid

Produkt 1

HCID 248874124-Methylnaphthalene-1-carbonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 0.35 g (1.89 mmol) of 4-methyl-1-napthoic acid in 3 mL of dry dichloromethane under argon, was added 2.5 ml (34.3 mmol) of thionyl chloride. The solution was refluxed for 4 hrs and the solvent and excess thionyl chloride were removed by vacuum distillation to give a red oil, which was used without further purification.

Aufarbeitung

  1. temperatureThe solution was refluxed for 4 hrs
  2. customthe solvent and excess thionyl chloride were removed by vacuum distillation
  3. customto give a red oil, which
  4. customwas used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-e7bf472ec26c4ba8bd4fa69a29f493ff
Quelldatensatz
uspto-grants-2015_05
Patentnummer
US09034895B2

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