Trifluoroacetic acid → Trifluoroacetic acid
Reaktionsgleichung
CC(OC([NH:8][CH2:9][CH:10]1[CH2:15][CH2:14][CH:13]([OH:16])[CH2:12][CH2:11]1)=O)(C)C.[F:17][C:18]([F:23])([F:22])[C:19]([OH:21])=[O:20]>ClCCl>[NH2:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([OH:16])[CH2:12][CH2:11]1.[F:17][C:18]([F:23])([F:22])[C:19]([OH:21])=[O:20]Komponenten
5
Edukt 2
Produkt 2
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Tert-butyl ((1r,4r)-4-hydroxycyclohexyl)methylcarbamate (1 g) in dichloromethane (10 mL) was treated with trifluoroacetic acid (5 mL) at 0° C. for 10 minutes and at room temperature for 30 minutes. The reaction mixture was concentrated and dried in vacuo to provide the title compound as a trifluoroacetic acid salt.
Aufarbeitung
- concentrationThe reaction mixture was concentrated
- customdried in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-abcd9976f0a14dfc99e10ac6f7c625bb
- Quelldatensatz
- uspto-grants-2015_05
- Patentnummer
- US09034875B2
Notizen zur Reaktion
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