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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 575394Erstellt: 24. Oktober 2026

Dichloromethane → HCID 178513779, Verbindung

https://huagongshe.com/de/reaction/575394

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDichloromethaneHCID 6344—
EduktHydrazineHCID 9321—
EduktCyclopropanecarboximidamide hydrochlorideHCID 2781916—
Edukt10-Bromo-3-iodo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamideHCID 86693191—
ProduktHCID 178513779HCID 17851377931%

Reaktionsschritte

10-bromo-3-(3-cyclopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide was prepared similarly according to Procedure I. Cyclopropylcarboxamidine hydrochloride was reacted with 10-bromo-3-iodo-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2-carboxamide then hydrazine. The completed reaction was then diluted with methylene chloride and filtered over celite to afford 83 mg (31% yield) of the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09034866B2
Quelldatensatzuspto-grants-2015_05
ORD IDord-8d6fb55e07f146a7ad8eb62fa058d146
Quellennotizuspto-grants-2015_05