HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Tert-butyl-5-(4-methylpiperazin-1-yl)-6-nitrobenzothiazole → 6-Amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Tert-butyl-5-(4-methylpiperazin-1-yl)-6-nitrobenzothiazole | HCID 19794200 | — |
| Katalysator | Nickel | HCID 935 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 6-Amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole | HCID 19794176 | — |
Reaktionsschritte
A solution of 86 g of the above nitro compound in 150 ml of ethanol is hydrogenated in presence of 30 g of Raney nickel at 45°. The solution is filtered to give 6-amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole, melting at 130° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05246927 |
| Quelldatensatz | uspto-grants-1993_09 |
| ORD ID | ord-c4b9469cd7684e858e4abf2ec83970cc |
| Quellennotiz | uspto-grants-1993_09 |