Methanol → AC-Pro-ome

HRID 579827Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 579827
CCCCCCCCCCCCCCC.C[OH:17].[C:18]([N:21]1[CH2:25][CH2:24][CH:23]=[CH:22]1)(=[O:20])[CH3:19].[O:26]1[CH2:30]CC[CH2:27]1>>[CH3:27][O:26][C:30](=[O:17])[C@@H:22]1[CH2:23][CH2:24][CH2:25][N:21]1[C:18](=[O:20])[CH3:19]

Komponenten

5

Edukt 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 12391PentadecaneHCID 10909522N-Acetyl-2-pyrroline2×

Produkt 1

HCID 11019314AC-Pro-omeAusbeute 4,1 %

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

A 70 ml stainless steel high pressure reactor having a Pyrex glass liner and a magnetic stir bar was charged with 5 mL of tetrahydrofuran, 0.5 mmol of n-pentadecane internal standard, 0.5 mmol of CH3OH, 10.0 mg of Co2 (CO)6 (PPh3)2, and 55.0 mg of N-acetyl-2-pyrroline. The reactor was pressurized with 1320 psi of CO and 300 psi of H2 at room temperature, and the reaction mixture was stirred at 100° C. for 21.75 hours. Thereafter, the reactor was cooled to room temperature and vented to atmospheric pressure. The product mixture was analyzed by gas chromatography, and the analysis indicated 76.6% conversion of N-acetyl-2-pyrroline and 4.1% yield of N-acetylproline methyl ester.

Aufarbeitung

  1. customA 70 ml stainless steel high pressure reactor having
  2. customwas pressurized with 1320 psi of CO and 300 psi of H2 at room temperature
  3. temperatureThereafter, the reactor was cooled to room temperature

Quellen und Nachweise

ORD-Eintrag
ord-2e52c745d8674c228c63de238422aa25
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04749786

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